WS19.4 Glucose and insulin area under the curve (AUC) can differentiate between cystic fibrosis patients that may benefit from early insulin treatment
نویسندگان
چکیده
منابع مشابه
Clinical improvement in cystic fibrosis with early insulin treatment.
Diabetes mellitus is an increasingly prevalent complication of cystic fibrosis (CF) as a result of the increased life expectancy resulting from advances in CF treatment. The management of cystic fibrosis related diabetes (CFRD) has previously focused on symptomatic relief under the assumption that, with limited life expectancy, aggressive treatment was unnecessary. However, there is now evidenc...
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BACKGROUND Management of postprandial hyperglycemia is a key aspect in diabetes treatment. We developed a novel system to measure glucose area under the curve (AUC) using minimally invasive interstitial fluid extraction technology (MIET) for simple monitoring of postprandial glucose excursions. In this study, we evaluated the relationship between our system and continuous glucose monitoring (CG...
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Early insulin response to rapid intravenous injection of glucose was studied in 7 cases of cystic fibrosis aged 8 months to 9 1/2 years. Plasma insulin was measured with a radioimmunological method. Blood glucose values were determined and the glucose disappearance rate (kG) calculated. In all children except the youngest one the early insulin response values were low compared with normal child...
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The aim of this study was to determine if once daily insulin detemir reverses decline in weight and lung function in patients with cystic fibrosis (CF). 12 patients with early insulin deficiency and six with CF related diabetes (aged 7.2-18.1 years) were treated for a median of 0.8 years. Changes in weight and lung function following treatment were compared to pretreatment changes. Before treat...
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Interest in the effects of insulin on the heart came with the recognition that hyperglycemia in the context of myocardial infarction is associated with increased risks of mortality, congestive heart failure, or cardiogenic shock.1–3 More recently, instigated by research findings on stress hyperglycemia in critical illness, this interest has been extended to the influence of insulin on clinical ...
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ژورنال
عنوان ژورنال: Journal of Cystic Fibrosis
سال: 2018
ISSN: 1569-1993
DOI: 10.1016/s1569-1993(18)30229-7